TECHNOLOGY

Autologous Muscle Tissue Regeneration

 
MUVON Therapeutics, tissue engineering
Biopsy

In a first step a small muscle biopsy taken from the patient under local anesthesia.

MUVON Therapeutics, muscle tissue regeneration
Expansion

The dormant muscle stem cells, which are located at the base of muscle fibers, are isolated from the surrounding tissue. During this process, they are activated and start proliferating into MPCs. These cells are expanded under strictly monitored conditions. Once, the required cell number is reached, the cells are harvested.

Quality Control

The quality of these cells is tested by an external, certified laboratory before the product is released.

Quality-Control MUVON Therapeutics Swiss biotechnology startup
Injection

The final product is prepared and transported to the hospital where it is injected into the damaged muscle of the patient.

Regeneration

Once injected, the MPCs begin to differentiate, form new muscle fibers and connect with existing muscle tissue leading to regeneration of the muscle. This regeneration is further supported by electromagnetic stimulation.

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DEVELOPMENT

For over a decade, pre-clinical and Proof of Concept studies were conducted in the tissue engineering laboratory of Prof. Eberli at the University of Zurich. Based on these results, the Swiss authorities gave their approval for a phase I clinical trial.

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PoC
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GMP
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GCP
 
 

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MUVON Therapeutics AG

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